ABSTRACT
A progressively diminishing capacity of eye to visualize for close proximity increasing by age is known as presbyopia which is usually resulted due to loss of elasticity of crystalline lens. A clinical trial was conducted to evaluate the efficacy of coded herbal formulation "ocucure" [Test drug] for the treatment of presbyopia comparing with leutivit [Placebo]. One hundred and eleven patients suffering from presbyopia from both groups [Males: 63, mean age: 34 +/- 14 and females: 48, mean age: 33 +/- 13 year, range: 20-60] were enrolled in the trial and divided in to two groups according to treatment regimens. Ocucure [Test drug] 500mg two tablets and leutivit [Placebo] 250mg tablets twice daily were prescribed for 6-8 weeks. Presbyopia was improved in 17 patients [28.81%] out of 59 patients by the use of ocucure [Test drug], and in 6 patients [11.53%] out of 52 by the use of leutivit [Control drug]. Furthermore, there was a significant improvement in presbyopic associated clinical features as compared to leutivit. It is concluded that ocucure possesses a therapeutic value for the improvement of presbyopia and its associated symptoms as compared to leutivit